Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15537163 | 1.00 | KCNH2 (0.58) | KCNH2SLC22A1TSHRHIF1AALDH1A1 | |
| Tetrahexylammonium SCHEMBL5052852 | 1.00 | KCNH2 (0.58) | KCNH2SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL701872 | 1.00 | KCNH2 (0.58) | KCNH2SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL15537986 | 1.00 | KCNH2 (0.58) | KCNH2SLC22A1TSHRHIF1AALDH1A1 | |
| Tetrabuthylammonium SCHEMBL15537506 | 0.94 | KCNH2 (0.51) | KCNH2SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL15539393 | 0.89 | KCNH2 (0.47) | KCNH2TP53SMN1; SMN2DNM1HTT | |
| SCHEMBL8569205 | 0.83 | SLC22A1 (0.50) | KCNH2SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL15538787 | 0.81 | PSMD14 (0.51) | KCNH2SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL15537740 | 0.81 | PSMD14 (0.51) | KCNH2SLC22A1TSHRHIF1AALDH1A1 | |
| SCHEMBL15538817 | 0.81 | SLC22A1 (0.52) | KCNH2SLC22A1TSHRHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050006237-A1 | Ion-selective solid-state polymeric membrane electrondes | REGENTS OF THE UNIVERSITY OF MICHIGAN | 2005-01-13 | — | — | US | disclosed |
| EP-1287345-A2 | ION-SELECTIVE SOLID-STATE POLYMERIC MEMBRANE ELECTRODES | MEDTRONIC, INC. (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001088520-A2 | ION-SELECTIVE SOLID-STATE POLYMERIC MEMBRANE ELECTRODES | MEDTRONIC, INC. (US) | 2001-11-22 | — | — | WO | disclosed |