Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16269355 | 0.84 | TAAR1 (0.62) | CYP1A2CYP2D6CYP2C19TAAR1SIGMAR1 | |
| SCHEMBL6183546 | 0.82 | CYP1A2 (0.76) | CYP1A2CYP2D6CYP2C19TAAR1LMNA | |
| SCHEMBL6365430 | 0.81 | CHRM2 (0.61) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL455309 | 0.80 | MEN1 (0.59) | MEN1KMT2AHTTSIGMAR1 | |
| SCHEMBL19633152 | 0.79 | CYP1A2 (0.88) | CYP1A2CYP2D6CYP2C19TAAR1LMNA | |
| SCHEMBL29672948 | 0.78 | CYP1A2 (0.65) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL8583518 | 0.78 | CYP1A2 (0.65) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL1420648 | 0.77 | CYP1A2 (0.62) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL3565819 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL4717200 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846953-B1 | Aromatic amides | WARNER LAMBERT COMPANY (US) | 2005-01-25 | — | — | US | claimed |
| EP-1178953-B1 | AROMATIC AMIDES | WARNER LAMBERT CO (US) | 2003-12-03 | — | — | EP | claimed |
| JP-2002544186-A | — | — | 2002-12-24 | — | — | JP | claimed |
| CN-1352631-A | Aromatic amides | WARNER LAMBERT CO (US) | 2002-06-05 | — | — | CN | claimed |
| EP-1178953-A1 | AROMATIC AMIDES | WARNER-LAMBERT COMPANY (US) | 2002-02-13 | — | — | EP | claimed |
| WO-2000068184-A1 | AROMATIC AMIDES | WARNER-LAMBERT COMPANY (US) | 2000-11-16 | — | — | WO | claimed |
| WO-2005121319-A1 | METHODS FOR PRODUCTION OF MESODERMAL LINEAGE CELLS | NOVATHERA LTD (GB) | 2005-12-22 | — | — | WO | disclosed |
| US-6846953-B1 | Aromatic amides | WARNER LAMBERT COMPANY (US) | 2005-01-25 | — | — | US | disclosed |