Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 14/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 14/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 14/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 14/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 14/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 14/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21370573 | 1.00 | LPL (0.52) | LPLLIPGPSEN1PSEN2APH1B | |
| SCHEMBL16108681 | 1.00 | LPL (0.52) | LPLLIPGPSEN1PSEN2APH1B | |
| SCHEMBL15947138 | 1.00 | LPL (0.52) | LPLLIPGPSEN1PSEN2APH1B | |
| SCHEMBL16390584 | 1.00 | LPL (0.52) | LPLLIPGPSEN1PSEN2APH1B | |
| SCHEMBL6858555 | 1.00 | LPL (0.52) | LPLLIPGPSEN1PSEN2APH1B | |
| SCHEMBL17445277 | 1.00 | LPL (0.52) | LPLLIPGPSEN1PSEN2APH1B | |
| SCHEMBL28051334 | 0.94 | PSEN1 (0.50) | LPLLIPGPSEN1PSEN2APH1B | |
| SCHEMBL15106752 | 0.92 | LPL (0.47) | LPLLIPGPSEN1PSEN2APH1B | |
| SCHEMBL12610372 | 0.89 | LPL (0.52) | LPLLIPGPSEN1PSEN2APH1B | |
| SCHEMBL29395862 | 0.89 | LPL (0.52) | LPLLIPGPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | SHEFFIELD, THE UNIVERSITY OF (GB) | 2005-06-02 | — | — | US | claimed |
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | SHEFFIELD, THE UNIVERSITY OF (GB) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | CBR3, OR10J3, ORC3 | LPL 4800/4885LIPG 4714/4885PSEN1 3918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.