Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 13/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6372767 | 0.85 | ADRA1A (0.53) | ADRA1AADRA1DADRA1B | |
| SCHEMBL6366508 | 0.85 | ADRA1A (0.51) | ADRA1AADRA1DADRA1BNISCH | |
| SCHEMBL6367347 | 0.82 | ADRA1A (0.36) | ADRA1AADRA1DADRA1BNISCH | |
| SCHEMBL6371214 | 0.82 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BNISCH | |
| SCHEMBL6367351 | 0.82 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BNISCH | |
| SCHEMBL6366600 | 0.81 | ADRA1A (0.40) | ADRA1AADRA1DADRA1BNISCH | |
| SCHEMBL6367364 | 0.81 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BNISCH | |
| SCHEMBL6367811 | 0.80 | TAAR1 (0.40) | ADRA1AADRA1DADRA1BNISCH | |
| SCHEMBL6367329 | 0.80 | ADRA1A (0.51) | ADRA1AADRA1DADRA1BNISCH | |
| SCHEMBL6366663 | 0.79 | ADRA1A (0.55) | ADRA1AADRA1DADRA1BNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884801-B1 | Imidazoline derivatives as alpha-1A adrenoceptor ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |