SCHEMBL636620

SCHEMBL636620

Cc1cccc(NC(=O)OOC(C)(C)C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.56
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
HPGD P15428 1/20 0.55
ALDH1A1 P00352 4/20 0.55
MAPK1 P28482 2/20 0.55
FAAH O00519 1/20 0.55
CYP3A4 P08684 1/20 0.55
RXFP1 Q9HBX9 1/20 0.51
NPSR1 Q6W5P4 1/20 0.50
LMNA P02545 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TP53 P04637 1/20 0.48
NFKB1 P19838 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28586148 0.91 HSD17B10 (0.53) HSD17B10KMT2AMEN1HPGDALDH1A1
SCHEMBL23581565 0.84 HSD17B10 (0.59) HSD17B10KMT2AMEN1HPGDALDH1A1
SCHEMBL29991501 0.84 HSD17B10 (0.59) HSD17B10KMT2AMEN1HPGDALDH1A1
SCHEMBL8966117 0.84 HSD17B10 (0.59) HSD17B10KMT2AMEN1HPGDALDH1A1
SCHEMBL13979800 0.82 ALDH1A1 (0.55) HSD17B10KMT2AMEN1HPGDALDH1A1
SCHEMBL2095614 0.80 ALDH1A1 (0.79) HSD17B10KMT2AMEN1HPGDALDH1A1
SCHEMBL30589563 0.80 ALDH1A1 (0.79) HSD17B10KMT2AMEN1HPGDALDH1A1
SCHEMBL4804898 0.78 ALDH1A1 (0.67) HSD17B10KMT2AMEN1HPGDALDH1A1
SCHEMBL10192054 0.77 MEN1 (0.61) HSD17B10KMT2AMEN1HPGDALDH1A1
SCHEMBL3399705 0.77 HDAC8 (0.54) HSD17B10KMT2AMEN1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US claimed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US claimed
CN-115469508-A Pattern forming method and method for producing curable composition 东京应化工业株式会社 2022-12-13 CN disclosed
EP-3449315-B1 RADIATION CURABLE DRY TONER AND METHOD FOR PREPARING THE SAME XEIKON MFG NV (BE) 2021-03-31 EP disclosed
US-10421828-B2 Resin composition for solid polymer fuel cell sealing material and solid polymer fuel cell sealing material using said resin composition PANAC CO., LTD. (JP) 2019-09-24 US disclosed
US-10310396-B2 Method of producing toner CANON KABUSHIKI KAISHA (JP) 2019-06-04 US disclosed
US-20190129322-A1 Radiation Curable Dry Toner and Method for Preparing the Same XEIKON MANUFACTURING N.V. (BE) 2019-05-02 US disclosed
US-20180329322-A1 METHOD OF PRODUCING TONER CANON KABUSHIKI KAISHA (JP) 2018-11-15 US disclosed
US-20170335026-A1 RESIN COMPOSITION FOR SOLID POLYMER FUEL CELL SEALING MATERIAL AND SOLID POLYMER FUEL CELL SEALING MATERIAL USING SAID RESIN COMPOSITION PANAC CO., LTD. (JP) 2017-11-23 US disclosed
US-20130143152-A1 CARRIER AND DEVELOPER FOR ELECTROSTATIC IMAGE DEVELOPMENT, AND IMAGE FORMATION METHOD AND APPARATUS FUJI XEROX CO., LTD. (JP) 2013-06-06 US disclosed
US-8288493-B2 (meth)acrylic-modified siloxane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-16 US disclosed
US-20070166636-A1 Electrophotographic toner and electrophotographic developer and image forming method FUJI XEROX CO., LTD. (JP) 2007-07-19 US disclosed
US-20070020552-A1 Carrier and developer for electrostatic image development, and image formation method and apparatus FUJI XEROX CO., LTD. (JP) 2007-01-25 US disclosed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US disclosed
EP-1655323-A2 Toner composition Xerox Corporation (US) 2006-05-10 EP disclosed
US-6942953-B2 Image forming method FUJI XEROX CO., LTD. (JP) 2005-09-13 US disclosed
US-20050175920-A1 Electrophotographic toner and production method therefor FUJI XEROX CO. LTD. (JP) 2005-08-11 US disclosed
US-20040253530-A1 Image forming method FUJI XEROX CO., LTD. (JP) 2004-12-16 US disclosed
US-6582867-B2 A crystalline binder resin and a fatty acid ester or a resin having a contact angle with water that is smaller than that of the crystalline resin; electrography; reproducibility in particle size/distribution; low-temperature fixing; stability FUJI XEROX CO., LTD. (JP) 2003-06-24 US disclosed
US-20020055050-A1 Toner for developing electrostatic latent image, process for producing the same, and process for forming image FUJI XEROX CO., LTD. (JP) 2002-05-09 US disclosed