⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14262048 | 1.00 | — | — | |
| SCHEMBL24433790 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6045189 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6045184 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6045182 | 0.97 | — | — | |
| SCHEMBL21482195 | 0.78 | GABRR1 (0.36) | — | |
| SCHEMBL28088986 | 0.78 | GABBR2 (0.39) | — | |
| SCHEMBL456709 | 0.78 | — | — | |
| SCHEMBL21114361 | 0.78 | GABRR1 (0.65) | — | |
| SCHEMBL9611232 | 0.78 | GABRR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824836-A | Workability is good, wide adaptability polycarboxylate water-reducer and preparation method thereof | 广东瑞安科技实业有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-101675053-B | Phosphoinositide 3-kinase inhibitor compounds and methods of use | GENENTECH INC | 2014-03-12 | — | — | CN | claimed |
| CN-1764457-A | Combination therapy for the treatment of Alzheimer's disease | MERCK SHARP & DOHME (GB) | 2006-04-26 | — | — | CN | claimed |
| US-20040220264-A1 | Bioavailability and improved delivery of acidic pharmaceutical drugs | YU RUEY J | 2004-11-04 | — | — | US | claimed |
| US-5877212-A | HYDROGEN BONDING WITH COMPLEXING AGENT | YU RUEY J (US) | 1999-03-02 | — | — | US | claimed |
| EP-0665747-A4 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE. | MERCK & CO INC (US) | 1995-11-15 | — | — | EP | claimed |
| EP-0665747-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO. INC. (US) | 1995-08-09 | — | — | EP | claimed |
| US-5073624-A | Therapeutic decapeptides | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1991-12-17 | — | — | US | claimed |
| US-4866160-A | Therapeutic decapeptides | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1989-09-12 | — | — | US | claimed |
| EP-0225746-A2 | Therapeutic decapeptides | The Administrators of The Tulane Educational Fund (US) | 1987-06-16 | — | — | EP | claimed |
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| CN-117750974-A | Viral vaccine | 生物技术欧洲股份公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-116194477-A | Binding agents to coronavirus S proteins | 生物技术欧洲股份公司 | 2023-05-30 | — | — | CN | disclosed |
| US-20230142285-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
| US-20220106327-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-07 | — | — | US | disclosed |
| US-4866160-A | Therapeutic decapeptides | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1989-09-12 | — | — | US | disclosed |
| US-4866160-A | Therapeutic decapeptides | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1989-09-12 | — | — | US | disclosed |
| EP-0225746-A2 | Therapeutic decapeptides | The Administrators of The Tulane Educational Fund (US) | 1987-06-16 | — | — | EP | disclosed |
| EP-0225746-A2 | Therapeutic decapeptides | The Administrators of The Tulane Educational Fund (US) | 1987-06-16 | — | — | EP | disclosed |
| US-4206143-A | Method for making N-substituted acrylamides and methacrylamides | ROHM GMBH (DE) | 1980-06-03 | — | — | US | disclosed |