Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citenamide SCHEMBL29446009 | 1.00 | ATM (0.57) | ATMLMNAHTR2AALDH1A1GAA | |
| SCHEMBL22418385 | 0.88 | ATM (0.46) | ATMLMNAHTR2AALDH1A1GAA | |
| SCHEMBL25220570 | 0.87 | ATM (0.44) | ATMLMNAHTR2AALDH1A1GAA | |
| SCHEMBL11710445 | 0.87 | ATM (0.44) | ATMLMNAHTR2AALDH1A1GAA | |
| SCHEMBL8797292 | 0.80 | HTR2A (0.43) | ATMLMNAHTR2AALDH1A1TSHR | |
| SCHEMBL13955533 | 0.79 | ATM (0.38) | ATMLMNAHTR2AALDH1A1GAA | |
| SCHEMBL12143285 | 0.78 | HTR2A (0.47) | ATMLMNAHTR2AALDH1A1GAA | |
| SCHEMBL3143561 | 0.77 | ATM (0.61) | ATMLMNAHTR2AALDH1A1GAA | |
| SCHEMBL30250175 | 0.77 | ATM (0.61) | ATMLMNAHTR2AALDH1A1GAA | |
| SCHEMBL6918423 | 0.76 | ATM (0.46) | ATMLMNAALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| EP-2672958-A1 | COMPOSITION AND LIPID FORMULATION OF A HYALURONAN-DEGRADING ENZYME AND THE USE THEREOF FOR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | Halozyme, Inc. (US) | 2013-12-18 | — | — | EP | claimed |
| US-8268352-B2 | Modified release composition for highly soluble drugs | TORRENT PHARMACEUTICALS LIMITED (IN) | 2012-09-18 | — | — | US | claimed |
| US-8263125-B2 | Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients | TORRENT PHARMACEUTICALS LIMITED (IN) | 2012-09-11 | — | — | US | claimed |
| WO-2012109387-A1 | COMPOSITION AND LIPID FORMULATION OF A HYALURONAN-DEGRADING ENZYME AND THE USE THEREOF FOR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | HALOZYME, INC. (US) | 2012-08-16 | — | — | WO | claimed |
| US-7939104-B2 | Granulation; compaction; rapid dissolution upon contact with physiological solvents such as water, saliva or gastrointestinal fluids | SANDOZ AG (CH) | 2011-05-10 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| US-7607596-B1 | Process for enhancing the solubility of poorly soluble drugs | Exxpharma, LLC (US) | 2009-10-27 | — | — | US | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| US-20080146581-A1 | Solubility of hydrophobic drugs with a compound having a carboxylic acid moiety | SANDOZ AG (CH) | 2008-06-19 | — | — | US | claimed |
| EP-1915136-A2 | COATED TABLES WITH ZERO-ORDER OR NEAR ZERO-ORDER RELEASE KINETICS | Metrics, Inc. (US) | 2008-04-30 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| WO-2007014061-A2 | COATED TABLES WITH ZERO-ORDER OR NEAR ZERO-ORDER RELEASE KINETICS | METRICS, INC. (US) | 2007-02-01 | — | — | WO | claimed |
| US-20070020331-A1 | Coated tablet with zero-order of near zero-order release kinetics | CATALENT GREENVILLE, INC. | 2007-01-25 | — | — | US | claimed |
| US-20060024365-A1 | Novel dosage form | VAYA NAVIN | 2006-02-02 | — | — | US | claimed |
| US-20060018933-A1 | Novel drug delivery system | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-01-26 | — | — | US | claimed |
| US-20060018934-A1 | Novel drug delivery system | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-01-26 | — | — | US | claimed |
| US-20050249814-A1 | Solubility of hydrophobic drugs with a compound having a carboxylic acid moiety | SANDOZ AG (CH) | 2005-11-10 | — | — | US | claimed |
| US-20050008704-A1 | Pharmaceutical composition for solubility enhancement of hydrophobic drugs | RAY ANUP KUMAR (US) | 2005-01-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146581-A1 | Solubility of hydrophobic drugs with a compound having a carboxylic acid moiety | ABCG2, ABCB11, SLC10A1 | ATM 4198/4885LMNA 4775/4885HTR2A 2410/4885 |
| US-20050249814-A1 | Solubility of hydrophobic drugs with a compound having a carboxylic acid moiety | ABCG2, ABCB11, SLC10A1 | ATM 4198/4885LMNA 4775/4885HTR2A 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.