Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | EEF2K | O00418 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287324 | 0.89 | MEN1 (0.57) | ALDH1A1ATML3MBTL1EEF2KMMP2 | |
| SCHEMBL27639242 | 0.89 | ALDH1A1 (0.52) | ALDH1A1ATML3MBTL1EEF2KMMP2 | |
| SCHEMBL1287456 | 0.89 | MEN1 (0.57) | ALDH1A1ATML3MBTL1EEF2KMMP2 | |
| SCHEMBL8842173 | 0.89 | KMT2A (0.58) | ALDH1A1ATML3MBTL1EEF2KMMP2 | |
| SCHEMBL15387943 | 0.89 | MEN1 (0.57) | ALDH1A1ATML3MBTL1EEF2KMMP2 | |
| SCHEMBL3199799 | 0.89 | ALDH1A1 (0.52) | ALDH1A1ATML3MBTL1EEF2KMMP2 | |
| SCHEMBL1287460 | 0.85 | SLC1A3 (0.53) | EEF2KSLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL28404274 | 0.83 | ATM (0.76) | ALDH1A1ATML3MBTL1EEF2KKMT2A | |
| SCHEMBL7207108 | 0.82 | GBA1 (0.51) | ALDH1A1ATML3MBTL1EEF2KMMP2 | |
| SCHEMBL5651951 | 0.80 | EEF2K (0.59) | ALDH1A1ATML3MBTL1EEF2KSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120270902-A1 | N-substituted benzene sulfonamides | ELAN PHARMACEUTICALS, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-8193389-B2 | N-substituted benzene sulfonamides | ELAN PHARMACEUTICALS, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-20050245573-A1 | N-substituted benzene sulfonamides | ELAN PHARMACEUTICALS, INC. | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245573-A1 | N-substituted benzene sulfonamides | PSEN1, PSEN2, BCHE | ALDH1A1 665/4885ATM 1881/4885L3MBTL1 2429/4885 |
| US-20120270902-A1 | N-substituted benzene sulfonamides | PSEN1, PSEN2, BCHE | ALDH1A1 665/4885ATM 1881/4885L3MBTL1 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.