SCHEMBL6367153

SCHEMBL6367153

CCCC1CCC(C2CCC(c3ccc(Cc4cccc(N)c4)cc3N)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
CYP19A1 P11511 1/20 0.33
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
PARP1 P09874 1/20 0.31
GRM2 Q14416 1/20 0.31
GRM3 Q14832 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6363955 0.92 GRM2 (0.34) CYP2C9CA1CA2CA9MAPT
SCHEMBL6363296 0.91 GRM2 (0.36) CYP2C9CA1CA2CA9MAPT
SCHEMBL6362621 0.91 GRM2 (0.36) CYP2C9CA1CA2CA9MAPT
SCHEMBL6362211 0.91 GRM2 (0.36) CYP2C9CA1CA2CA9MAPT
SCHEMBL6363303 0.90 CYP2C9 (0.36) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7732440 0.90 CYP2C9 (0.36) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL6367676 0.85 CA1 (0.37) CA1CA2CA9ALDH1A1CYP19A1
SCHEMBL6751229 0.84 CA1 (0.38) CA1CA2CA9ALDH1A1MAPT
SCHEMBL6367773 0.82 CYP3A4 (0.33) CYP2C9ALDH1A1MAPTMEN1KMT2A
SCHEMBL6752073 0.81 MAPT (0.34) CYP2C9ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6949281-B1 Varnish composition and liquid-crystal display element CHISSO CORPORATION (JP) 2005-09-27 US disclosed
US-6746730-B1 VARNISH COMPOSITION WHICH COMPRISES POLYMER COMPONENT CONTAINING TWO DIFFERENT POLYAMIC ACIDS, SOLUBLE POLYIMIDE, AND SOLVENT FOR DISSOLVING POLYMER COMPONENT CHISSO CORPORATION (JP) 2004-06-08 US disclosed