SCHEMBL7732440

SCHEMBL7732440

CCCC1CCC(C2CCC(C3CCC(c4ccc(Cc5ccc(N)cc5)cc4N)CC3)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
MEN1 O00255 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
GAA P10253 1/20 0.31
OPRL1 P41146 3/20 0.30
TLR4 O00206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6363303 1.00 CYP2C9 (0.36) CYP2C9ALDH1A1CYP3A4TSHRTDP1
SCHEMBL6367773 0.92 CYP3A4 (0.33) CYP2C9ALDH1A1CYP3A4TSHRTDP1
SCHEMBL7733088 0.91 MAPT (0.34) CYP2C9ALDH1A1CYP3A4TSHRTDP1
SCHEMBL6752073 0.91 MAPT (0.34) CYP2C9ALDH1A1CYP3A4TSHRTDP1
SCHEMBL6362663 0.91 MAPT (0.34) CYP2C9ALDH1A1CYP3A4TSHRTDP1
SCHEMBL6367754 0.91 MAPT (0.34) CYP2C9ALDH1A1CYP3A4TSHRTDP1
SCHEMBL6367153 0.90 CYP2C9 (0.34) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945198 0.85 OPRL1 (0.40) CYP2C9ALDH1A1CYP3A4TSHRTDP1
SCHEMBL6363203 0.84 ALDH1A1 (0.39) ALDH1A1CYP3A4TSHRTDP1MAPT
SCHEMBL6363215 0.83 ALDH1A1 (0.40) ALDH1A1CYP3A4TSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6476266-B1 Diamino compound and production process for the same CHISSO CORPORATION (JP) 2002-11-05 US disclosed