Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | PTGES | O14684 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1322605 | 0.85 | ALOX5 (0.52) | ALOX5PTGESPPARGLMNACYP2C9 | |
| SCHEMBL5607169 | 0.85 | ALOX5 (0.52) | ALOX5PTGESPPARGLMNAHPGD | |
| SCHEMBL29741641 | 0.85 | ALOX5 (0.52) | ALOX5PTGESPPARGLMNAHPGD | |
| SCHEMBL8702152 | 0.85 | ALOX5 (0.59) | ALOX5PTGESPPARGLMNAMEN1 | |
| SCHEMBL1786246 | 0.85 | ALOX5 (0.59) | ALOX5PTGESPPARGLMNAMEN1 | |
| SCHEMBL524131 | 0.85 | ALOX5 (0.59) | ALOX5PTGESPPARGLMNAMEN1 | |
| SCHEMBL524132 | 0.85 | ALOX5 (0.59) | ALOX5PTGESPPARGLMNAMEN1 | |
| SCHEMBL6060200 | 0.83 | ALOX5 (0.49) | ALOX5TRPA1PTGESPPARGPSEN1 | |
| SCHEMBL4662670 | 0.83 | MEN1 (0.51) | TRPA1PPARGLMNAMEN1CYP1A2 | |
| SCHEMBL4662669 | 0.83 | MEN1 (0.51) | TRPA1PPARGLMNAMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050010068-A1 | Use of microencapsulated transition metal reagents for reactions in supercritical fluids | AVECIA LIMITED (GB) | 2005-01-13 | — | — | US | disclosed |
| EP-1453780-A1 | THE USE OF MICROENCAPSULATED TRANSITION METAL REAGENTS FOR REACTIONS IN SUPERCRITICAL FLUIDS | Avecia Limited (GB) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048090-A1 | THE USE OF MICROENCAPSULATED TRANSITION METAL REAGENTS FOR REACTIONS IN SUPERCRITICAL FLUIDS | AVECIA LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010068-A1 | Use of microencapsulated transition metal reagents for reactions in supercritical fluids | HPSE, SIK1, SGK1 | ALOX5 503/4885TRPA1 4170/4885PTGES 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.