Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 20/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 14/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 13/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL6366164 | 0.90 | ADRA1A (0.82) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| Fumaric Acid SCHEMBL6366170 | 0.90 | ADRA1A (0.82) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6372617 | 0.80 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6365965 | 0.80 | ADRA1A (0.97) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL17886788 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6371084 | 0.78 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL26078383 | 0.78 | ADRA1A (0.64) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6368360 | 0.78 | ADRA1A (0.97) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6372622 | 0.77 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6374061 | 0.77 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884801-B1 | Imidazoline derivatives as alpha-1A adrenoceptor ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |