Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368990 | 0.92 | TP53 (0.61) | TP53SMN1; SMN2USP2GAALMNA | |
| SCHEMBL6368197 | 0.86 | TP53 (0.64) | TP53SMN1; SMN2USP2GAALMNA | |
| SCHEMBL6368651 | 0.86 | TP53 (0.56) | TP53SMN1; SMN2USP2GAALMNA | |
| SCHEMBL6368668 | 0.86 | TP53 (0.59) | TP53SMN1; SMN2USP2GAALMNA | |
| SCHEMBL8292153 | 0.84 | TP53 (0.61) | TP53SMN1; SMN2USP2GAALMNA | |
| SCHEMBL6368875 | 0.84 | TP53 (0.61) | TP53SMN1; SMN2USP2GAALMNA | |
| SCHEMBL6368880 | 0.84 | TP53 (0.61) | TP53SMN1; SMN2USP2GAALMNA | |
| SCHEMBL6373299 | 0.83 | TP53 (0.60) | TP53SMN1; SMN2USP2GAALMNA | |
| SCHEMBL6369013 | 0.83 | SMN1; SMN2 (0.61) | TP53SMN1; SMN2USP2GAALMNA | |
| SCHEMBL6368940 | 0.83 | TP53 (0.59) | TP53SMN1; SMN2USP2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903075-B1 | Heterocyclic amide compounds as cell adhesion inhibitors | MERCK & CO., INC. (US) | 2005-06-07 | — | — | US | claimed |