SCHEMBL6368164

SCHEMBL6368164

N=C(N)NCCCC(N)C(=O)NC[C]=O

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.49
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
RRM1 P23921 1/20 0.42
NPY4R P50391 9/20 0.40
NPY1R P25929 5/20 0.40
NPY2R P49146 4/20 0.40
NPY5R Q15761 4/20 0.40
OTC P00480 1/20 0.38
NOD1 Q9Y239 1/20 0.37
NOS1 P29475 2/20 0.36
NOS3 P29474 1/20 0.36
NOS2 P35228 1/20 0.36
DDAH1 O94760 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6368171 1.00 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL1521349 1.00 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL2184148 0.90 DPP7 (0.43) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL1521599 0.90 DPP7 (0.43) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL1521366 0.89 DPP7 (0.42) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL18159136 0.86 DPP7 (0.47) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL1004635 0.86 DPP7 (0.47) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL1521379 0.86 DPP7 (0.47) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL23626315 0.85 DPP7 (0.61) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL23610947 0.85 DPP7 (0.61) DPP7GNAI3GNAO1GNAI1RRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545991-B1 PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF VAHLNE ANDERS (SE) 1998-12-02 EP claimed
EP-0143746-A2 5-Amino 4-hydroxy-valeryl-substituted derivatives CIBA-GEIGY AG (CH) 1985-06-05 EP claimed
EP-3987003-A1 SYSTEMS AND METHODS FOR FABRICATING A MICROCHANNEL VASCULAR NETWORK DEVICE AND SEEDING A MICROCHANNEL 3D Biolabs, LLC (US) 2022-04-27 EP disclosed
US-20210071145-A1 SYSTEMS AND METHODS FABRICATING A MICROCHANNEL VASCULAR NETWORK DEVICE AND SEEDING A MICROCHANNEL 3D BIOLABS, LLC 2021-03-11 US disclosed
WO-2020257539-A1 SYSTEMS AND METHODS FOR FABRICATING A MICROCHANNEL VASCULAR NETWORK DEVICE AND SEEDING A MICROCHANNEL 3D BIOLABS, LLC (US) 2020-12-24 WO disclosed
US-20050265989-A1 Non-toxic purification and activation of prothrombin and use thereof KALD FISK AS (NO) 2005-12-01 US disclosed
EP-0545991-B1 PEPTIDES THAT BLOCK HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS AND METHODS OF USE THEREOF VAHLNE ANDERS (SE) 1998-12-02 EP disclosed
US-5087564-A Preferential cleavage of an e coli rec a fusion protein at the clu-ser junction site of a heterologous peptide MONSANTO COMPANY (US) 1992-02-11 US disclosed
US-4863903-A RENIN ENZYME INHIBITORS, HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1989-09-05 US disclosed
US-4719288-A HYPOTENSIVE CIBA-GEIGY CORPORATION (US) 1988-01-12 US disclosed
EP-0207044-A1 Release of peptides from polypeptides Monsanto Company (US) 1986-12-30 EP disclosed
US-4613676-A PEPTIDES CIBA-GEIGY CORPORATION (US) 1986-09-23 US disclosed
EP-0143746-A2 5-Amino 4-hydroxy-valeryl-substituted derivatives CIBA-GEIGY AG (CH) 1985-06-05 EP disclosed