Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12482200 | 1.00 | LMNA (0.52) | LMNABCHEACHETSHRCYP3A4 | |
| SCHEMBL11957436 | 0.84 | LMNA (0.47) | LMNABCHEACHETSHRCYP3A4 | |
| SCHEMBL23219625 | 0.84 | LMNA (0.44) | LMNABCHEACHETSHRPOLB | |
| SCHEMBL6471382 | 0.80 | GAA (0.44) | TSHRCYP3A4MAPTCYP2C19POLB | |
| SCHEMBL7312317 | 0.80 | GAA (0.44) | TSHRCYP3A4MAPTCYP2C19POLB | |
| SCHEMBL1221080 | 0.80 | GAA (0.44) | TSHRCYP3A4MAPTCYP2C19POLB | |
| SCHEMBL27353845 | 0.78 | GAA (0.43) | TSHRCYP3A4MAPTCYP2C19POLB | |
| SCHEMBL9886347 | 0.78 | GLA (0.55) | — | |
| SCHEMBL9917628 | 0.78 | GLA (0.55) | — | |
| SCHEMBL4413019 | 0.78 | GLA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022194759-A1 | POLY(AMINO ACID) BASED CAPSULES | AGFA-GEVAERT NV (BE) | 2022-09-22 | — | — | WO | disclosed |
| US-8993686-B2 | Multiamino acid-based poly(ester amide)s | CORNELL UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-8993686-B2 | Multiamino acid-based poly(ester amide)s | CORNELL UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-20120123064-A1 | Multiamino Acid-Based Poly(Ester Amide)s | CORNELL UNIVERSITY (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120123064-A1 | Multiamino Acid-Based Poly(Ester Amide)s | CORNELL UNIVERSITY (US) | 2012-05-17 | — | — | US | disclosed |