Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 18/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 17/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 17/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 9/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.73 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL6368462 | 0.91 | ADRA1A (0.83) | ADRA1AADRA1DADRA1BADRA2AADRA2C | |
| Fumaric Acid SCHEMBL6368473 | 0.91 | ADRA1A (0.83) | ADRA1AADRA1DADRA1BADRA2AADRA2C | |
| SCHEMBL6315485 | 0.86 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRA2AADRA2C | |
| SCHEMBL6371025 | 0.85 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRA2AADRA2C | |
| SCHEMBL5612258 | 0.84 | ADRA1A (0.77) | ADRA1AADRA1DADRA1BADRA2AADRA2C | |
| Hydrochloric Acid SCHEMBL7576064 | 0.82 | ADRA1A (0.77) | ADRA1AADRA1DADRA1BADRA2AADRA2C | |
| SCHEMBL6365534 | 0.82 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRA2AADRA2C | |
| SCHEMBL6371153 | 0.81 | ADRA1A (0.76) | ADRA1AADRA1DADRA1BADRA2AADRA2C | |
| Hydrochloric Acid SCHEMBL6367759 | 0.81 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRA2AADRA2C | |
| SCHEMBL6436107 | 0.81 | ADRA1A (0.74) | ADRA1AADRA1DADRA1BADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884801-B1 | Imidazoline derivatives as alpha-1A adrenoceptor ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |