Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 5/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066497 | 0.88 | ITGB1 (0.56) | ITGA4ITGB1ITGA5ITGB7MMP1 | |
| SCHEMBL6372653 | 0.88 | POLB (0.55) | ITGA4ITGB1ITGA5ITGB7MMP1 | |
| SCHEMBL3850203 | 0.87 | ITGB1 (0.50) | ITGA4ITGB1ITGA5ITGB7MMP1 | |
| SCHEMBL7325939 | 0.86 | ITGB1 (0.48) | ITGA4ITGB1ITGA5ITGB7MMP1 | |
| SCHEMBL6368426 | 0.84 | ITGB1 (0.58) | ITGA4ITGB1ITGA5ITGB7MMP1 | |
| SCHEMBL6429378 | 0.84 | ITGB1 (0.67) | ITGA4ITGB1ITGA5ITGB7ITGAV | |
| SCHEMBL6714478 | 0.84 | ITGA4 (0.43) | ITGA4ITGB1ITGA5MMP1MMP2 | |
| SCHEMBL6429310 | 0.83 | ITGB1 (0.51) | ITGA4ITGB1ITGA5ITGB7ITGAV | |
| SCHEMBL3855802 | 0.83 | CACNA1B (0.46) | ITGA4ITGB1ITGA5ITGB7MMP1 | |
| SCHEMBL7067616 | 0.82 | POLB (0.50) | ITGA4ITGB1ITGA5ITGB7MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903075-B1 | Heterocyclic amide compounds as cell adhesion inhibitors | MERCK & CO., INC. (US) | 2005-06-07 | — | — | US | claimed |