SCHEMBL6368754

SCHEMBL6368754

[CH2]C(Cc1ccccc1O)Cc1ccccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.54
CYP2D6 P10635 2/20 0.48
TSHR P16473 2/20 0.48
HIF1A Q16665 2/20 0.48
TAAR1 Q96RJ0 1/20 0.46
AKR1B1 P15121 1/20 0.46
CA12 O43570 7/20 0.45
CA2 P00918 7/20 0.45
IDO1 P14902 2/20 0.45
CA9 Q16790 5/20 0.43
MPO P05164 1/20 0.43
KEAP1 Q14145 1/20 0.43
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
CYP3A4 P08684 2/20 0.42
KDM4E B2RXH2 2/20 0.42
HSD17B10 Q99714 2/20 0.42
NPC1 O15118 1/20 0.41
GMNN O75496 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9026107 0.82 HSPA5 (0.50) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL8931392 0.78 HSPA5 (0.56) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL3071437 0.76 HSPA5 (0.54) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL108067 0.76 GABRA1 (0.64) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL2060682 0.76 HSPA5 (0.54) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL11223294 0.76 HSPA5 (0.54) HSPA5CYP2D6TSHRHIF1ATAAR1
Formaldehyde SCHEMBL14742618 0.76 GABRA1 (0.57) HSPA5CYP2D6TSHRHIF1ATAAR1
Hydrochloric Acid SCHEMBL11780889 0.75 HSPA5 (0.59) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL3705105 0.74 HSPA5 (0.52) HSPA5CYP2D6TSHRHIF1ATAAR1
SCHEMBL983098 0.74 HSPA5 (0.52) HSPA5CYP2D6TSHRHIF1ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005122729-A2 AN IRON SEQUESTERING ANTIMICROBIAL COMPOSITION EASTMAN KODAK COMPANY (US) 2005-12-29 WO disclosed