Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 3/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6377106 | 1.00 | EPHX1 (0.47) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL623688 | 0.90 | EPHX1 (0.56) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL2639450 | 0.90 | EPHX1 (0.56) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL6486058 | 0.90 | EPHX1 (0.56) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL309963 | 0.90 | EPHX1 (0.56) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL7327748 | 0.90 | EPHX1 (0.56) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL8781479 | 0.88 | EPHX1 (0.54) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL5568008 | 0.88 | EPHX1 (0.54) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL24311844 | 0.81 | SRR (0.50) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL18647219 | 0.81 | SRR (0.50) | EPHX1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137141-A1 | Prodrug composition | HILFINGER JOHN (US) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137141-A1 | Prodrug composition | CYP3A5, SLC35B2, SLC1A5 | EPHX1 1951/4885ALPI 215/4885PKM 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.