Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278081 | 0.86 | PLK1 (0.52) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL19149288 | 0.86 | PLK1 (0.52) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6372020 | 0.86 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| Cetaben SCHEMBL2112078 | 0.86 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL11478101 | 0.86 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL10534588 | 0.86 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL11283832 | 0.86 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL10950807 | 0.86 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL22398313 | 0.86 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL11278167 | 0.86 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852480-B1 | Photographic material comprising a bicyclic pyrazolotriazole coupler with improved photographic properties | EASTMAN KODAK COMPANY (US) | 2005-02-08 | — | — | US | disclosed |
| US-6641990-B1 | Photographic films having light sensitive silver halide emulsion layers containing couplers, which react with dye developers to provide yellow, magenta and cyan colors and images | EASTMAN KODAK COMPANY | 2003-11-04 | — | — | US | disclosed |