Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 7/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370461 | 0.86 | ERAP1 (0.47) | FTOITGA4ITGB1CDK2ERAP1 | |
| SCHEMBL6373410 | 0.86 | ERAP1 (0.47) | FTOITGA4ITGB1CDK2ERAP1 | |
| SCHEMBL6365738 | 0.85 | ACE (0.42) | FTOPTPN1PPARGPPARDPPARA | |
| SCHEMBL6365732 | 0.85 | ACE (0.42) | FTOPTPN1PPARGPPARDPPARA | |
| SCHEMBL6370495 | 0.85 | MCL1 (0.39) | CDK2MCL1PTPN1PPARGPPARD | |
| SCHEMBL6370489 | 0.85 | MCL1 (0.39) | CDK2MCL1PTPN1PPARGPPARD | |
| SCHEMBL6372026 | 0.80 | CDK2 (0.53) | FTOITGA4ITGB7ITGB1CDK2 | |
| SCHEMBL6365927 | 0.80 | CDK2 (0.45) | FTOITGA4ITGB1CDK2ERAP1 | |
| SCHEMBL6366063 | 0.80 | ERAP1 (0.48) | FTOITGA4ITGB7ITGB1CDK2 | |
| SCHEMBL6365922 | 0.80 | CDK2 (0.45) | FTOITGA4ITGB1CDK2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272784-A1 | Inhibitors of bacterial Type III protein secretion systems | LI XIAOBING | 2005-12-08 | — | — | US | disclosed |
| WO-2005113522-A1 | AZOLE CARBOXAMIDE INHIBITORS OF BACTERIAL TYPE III PROTEIN SECRETION SYSTEMS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272784-A1 | Inhibitors of bacterial Type III protein secretion systems | GBA3, PSMB3, SEC61B | FTO 4883/4885ITGA4 4623/4885ITGB7 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.