SEC61B

Protein transport protein Sec61 subunit beta · P60468 · SEC61B on Sugi Atlas →

0 patent compounds predicted against SEC61B, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SEC61B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops PHASE2UNKNOWN
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers PHASE1/PHASE2RECRUITING
A Phase 2 Trial of SCO-101 in Combination With FOLFIRI for Patients With Metastatic Colorectal Cancer (mCRC) With Acquired Resistance to FOLFIRI PHASE1/PHASE2UNKNOWN
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
Phase I Study of Novel Estrogen Receptor(ER) a36 Modifier Icaritin in Advanced Breast Cancer Patients PHASE1UNKNOWN
A Phase Ib Study to Assess Safety and Efficacy of Oral Icaritin in Advanced Solid Tumors PHASE1COMPLETED
SNX-5422 to Treat Solid Tumor Cancers and Lymphomas PHASE1COMPLETED
A Phase I Study of Pyrimethamine in Patients With GM2 Gangliosidosis PHASE1WITHDRAWN
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Quantification of GADD34 Expression in RA nanCOMPLETED
Association Between Intakes of Protein, Calcium and Milk With Gene Expression and Linear Growth of School Aged Children nanCOMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Fatty Acids Lipidome and Oxidative Stress in Liver Transplantation nanUNKNOWN
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment. nanACTIVE_NOT_RECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
The Role of DNA and RNA in NGS Analyses for Advaced Stage NSCLC Patients nanRECRUITING
Surfactant Derived Protocol in Heart Failure nanCOMPLETED
Immunological Profile and Clinical Characteristics of Children Diagnosed With Chronic Granulomatous Disease nanUNKNOWN
Preliminary Study for Identification of Calcium-Binding Proteins in the Serum in Various Metabolic Bone Disorders nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma(SELINA) nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a SEC61B binder may also engage these)

ProteinNameSimilarity
P60467 1.000 P60467 →
Q5RB31 1.000 Q5RB31 →
Q9CQS8 1.000 Q9CQS8 →
A8I6P9 0.999 A8I6P9 →
Q8J2P4 0.996 Q8J2P4 →
P52871 0.993 P52871 →
P52870 0.992 P52870 →
P38389 0.991 P38389 →
O43002 0.991 O43002 →
Q8N6R1 0.990 Q8N6R1 →
Q9HFC7 0.989 Q9HFC7 →
Q32L85 0.989 Q32L85 →
Q8K190 0.989 Q8K190 →
Q6TAW2 0.989 Q6TAW2 →
Q6AX78 0.987 Q6AX78 →
Q28GG3 0.987 Q28GG3 →
Q5REZ1 0.987 Q5REZ1 →
Q3T073 0.986 Q3T073 →
P36795 0.986 P36795 →
P01307 0.986 P01307 →
Q64152 0.986 Q64152 →
P0C649 0.986 P0C649 →
BTF3 Transcription factor BTF3 0.985 landscape →
P50766 0.985 P50766 →
Q9FKV8 0.985 Q9FKV8 →
P9WL38 0.985 P9WL38 →
Q9Y6X1 0.985 Q9Y6X1 →
Q3ZBR1 0.985 Q3ZBR1 →
P03197 0.985 P03197 →
Q54YR4 0.985 Q54YR4 →