Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 17/20 | 0.98 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.79 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.63 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378090 | 0.99 | LTB4R (1.00) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL6373365 | 0.91 | LTB4R (1.00) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8583520 | 0.90 | LTB4R (0.83) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL8650764 | 0.88 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL6370354 | 0.88 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL8950060 | 0.87 | LTB4R (0.78) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL7625803 | 0.86 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9372183 | 0.86 | LTB4R (1.00) | LTB4RLTB4R2CYSLTR2CYSLTR1 | |
| SCHEMBL3679470 | 0.84 | LTB4R (1.00) | LTB4RLTB4R2 | |
| Sc-41390 SCHEMBL6372085 | 0.83 | LTB4R (0.98) | LTB4RLTB4R2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933272-B1 | Use of non-peptidyl compounds for the treatment of insulin related ailments | HELMERHORST ERIK (AU) | 2005-08-23 | — | — | US | disclosed |
| EP-1115422-A4 | USE OF NON-PEPTIDYL COMPOUNDS FOR THE TREATMENT OF INSULIN RELATED AILMENTS | UNIV CURTIN TECH (AU) | 2003-01-29 | — | — | EP | disclosed |
| EP-1115422-A1 | USE OF NON-PEPTIDYL COMPOUNDS FOR THE TREATMENT OF INSULIN RELATED AILMENTS | CURTIN UNIVERSITY OF TECHNOLOGY (AU) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000016798-A1 | USE OF NON-PEPTIDYL COMPOUNDS FOR THE TREATMENT OF INSULIN RELATED AILMENTS | CURTIN UNIVERSITY OF TECHNOLOGY (AU) | 2000-03-30 | — | — | WO | disclosed |
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |