Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.65 |
| ▸ | NQO2 | P16083 | 4/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076132 | 0.88 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL6075887 | 0.86 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL27544425 | 0.82 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL5343899 | 0.81 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL7830444 | 0.80 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6076561 | 0.79 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL8858530 | 0.79 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL6075773 | 0.77 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL6076556 | 0.77 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| Acetamide SCHEMBL7838095 | 0.74 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872851-B1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | LES LABORATORIES SERVIER (FR) | 2005-03-29 | — | — | US | disclosed |