Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | ESRRG | P62508 | 8/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ESRRB | O95718 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6373219 | 1.00 | ESR1 (0.65) | ESR1CYP19A1ESR2LMNAHTR6 | |
| SCHEMBL6373225 | 1.00 | ESR1 (0.65) | ESR1CYP19A1ESR2LMNAHTR6 | |
| SCHEMBL7109988 | 0.99 | ESR1 (0.66) | ESR1CYP19A1ESR2LMNAHTR6 | |
| SCHEMBL7519055 | 0.99 | ESR1 (0.66) | ESR1CYP19A1ESR2LMNAHTR6 | |
| SCHEMBL5727007 | 0.99 | ESR1 (0.66) | ESR1CYP19A1ESR2LMNAHTR6 | |
| SCHEMBL7109996 | 0.99 | ESR1 (0.66) | ESR1CYP19A1ESR2LMNAHTR6 | |
| Hydrochloric Acid SCHEMBL7205293 | 0.97 | ESR1 (0.65) | ESR1CYP19A1ESR2LMNAHTR6 | |
| SCHEMBL8362771 | 0.96 | ESR1 (0.63) | ESR1CYP19A1ESR2LMNAHTR6 | |
| SCHEMBL8362770 | 0.96 | ESR1 (0.63) | ESR1CYP19A1ESR2LMNAHTR6 | |
| SCHEMBL5726853 | 0.95 | ESR1 (0.72) | ESR1CYP19A1ESR2LMNAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891070-B2 | Method for the preparation of 2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]ethoxy}ethanol and its isomers | HORMOS MEDICAL CORPORATION (FI) | 2005-05-10 | — | — | US | disclosed |
| US-20040116538-A1 | Method for the preparation of 2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy}ethanol and its isomers | FORENDO PHARMA LTD. (FI) | 2004-06-17 | — | — | US | disclosed |
| EP-1383724-A1 | A NEW METHOD FOR THE PREPARATION OF 2- 2- 4-(4-CHLORO-1,2-DIPHENYLBUT-1-ENYL)PHENOXY]ETHOXY ETHANOL AND ITS ISOMERS | Hormos Medical Corporation (FI) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090305-A1 | A NEW METHOD FOR THE PREPARATION OF 2-{2-[4-(4-CHLORO-1,2-DIPHENYLBUT-1-ENYL)PHENOXY]ETHOXY}ETHANOL AND ITS ISOMERS | HORMOS MEDICAL CORPORATION (FI) | 2002-11-14 | — | — | WO | disclosed |