Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.43 |
| ▸ | PPARG | P37231 | 14/20 | 0.43 |
| ▸ | PPARD | Q03181 | 13/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386585 | 0.88 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL5399381 | 0.88 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL6375192 | 0.85 | PPARA (0.42) | PPARAPPARGPPARD | |
| SCHEMBL5569835 | 0.83 | HSD17B2 (0.43) | PPARAPPARGPPARD | |
| SCHEMBL3944558 | 0.80 | AOC3 (0.41) | PPARAPPARGPPARD | |
| SCHEMBL6620937 | 0.78 | PPARG (0.44) | PPARGTDP1 | |
| SCHEMBL3949115 | 0.77 | PPARG (0.39) | PPARAPPARGPPARD | |
| SCHEMBL3946840 | 0.77 | ABHD6 (0.41) | PPARAPPARGPPARD | |
| SCHEMBL3952266 | 0.77 | HSD17B2 (0.40) | PPARAPPARGPPARD | |
| SCHEMBL3949723 | 0.77 | HSD17B2 (0.40) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137238-A1 | Biaromatic ligand activators of PPARgamma receptors | GALDERMA RESEARCH & DEVELOPMENT S.N.C. | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137238-A1 | Biaromatic ligand activators of PPARgamma receptors | PPARG, PPARA, PPARD | PPARA 2/4885PPARG 1/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.