SCHEMBL6375294

SCHEMBL6375294

CN(C(=O)C=CCC(C)(C)N)[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)NN1C(C)(C)CCCC1(C)C

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 8/20 0.54
TACR1 P25103 3/20 0.34
TACR2 P21452 1/20 0.32
F2 P00734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6375275 1.00 GHSR (0.54) GHSRTACR1TACR2F2
SCHEMBL3266709 0.88 GHSR (0.57) GHSRTACR1
SCHEMBL13308041 0.88 GHSR (0.57) GHSRTACR1
SCHEMBL3266944 0.88 GHSR (0.57) GHSRTACR1
SCHEMBL3266691 0.87 GHSR (0.56) GHSRTACR1
SCHEMBL3266703 0.87 GHSR (0.56) GHSRTACR1
Tabimorelin SCHEMBL4435323 0.85 GHSR (0.65) GHSR
Tabimorelin SCHEMBL22345096 0.85 GHSR (0.65) GHSR
SCHEMBL6316843 0.85 GHSR (0.65) GHSR
Tabimorelin SCHEMBL13575741 0.85 GHSR (0.65) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919315-B1 Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 2005-07-19 US disclosed