Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081533 | 0.84 | HIF1A (0.57) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 | |
| SCHEMBL27979602 | 0.84 | MAPT (0.48) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 | |
| SCHEMBL28221517 | 0.82 | HIF1A (0.50) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 | |
| SCHEMBL8783850 | 0.80 | HIF1A (0.53) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 | |
| SCHEMBL2300536 | 0.80 | CYP2C19 (0.64) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 | |
| SCHEMBL7531200 | 0.80 | HIF1A (0.53) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 | |
| SCHEMBL2295046 | 0.80 | CYP2C19 (0.64) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 | |
| SCHEMBL167044 | 0.80 | CYP2C19 (0.64) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 | |
| SCHEMBL372277 | 0.80 | HIF1A (0.53) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 | |
| SCHEMBL15228093 | 0.80 | HIF1A (0.53) | HIF1ACYP2C19KCNN4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108834402-A | Method for generating tumor infiltrating T cell population | 莱特克斯生物制药股份有限公司 | 2018-11-16 | — | — | CN | disclosed |
| US-8119364-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100304430-A1 | Methods for Generating Analogs of Coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-7727738-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070128683-A1 | Metabolic delivery of coenzyme A analogs | NATIONAL SCIENCE FOUNDATION | 2007-06-07 | — | — | US | disclosed |
| EP-0057444-B1 | DICHLOROAMINO ACID DERIVATIVES USEFUL AS POTENT GERMICIDAL AND FUNGICIDAL AGENTS | MERCK & CO. INC. (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4386103-A | ENVIRONMENT, FOOD TREATMENT, PERSONAL OR VETERINARY HYGIENE | MERCK & CO., INC. (US) | 1983-05-31 | — | — | US | disclosed |
| EP-0057444-A2 | Dichloroamino acid derivatives useful as potent germicidal and fungicidal agents | MERCK & CO. INC. (US) | 1982-08-11 | — | — | EP | disclosed |