Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135132 | 0.91 | HRH3 (0.56) | HRH3PDE4DPDE7AALDH1A1ESR1 | |
| SCHEMBL6134442 | 0.90 | HRH3 (0.55) | HRH3PDE4DPDE7AALDH1A1ESR1 | |
| SCHEMBL64179 | 0.88 | HRH3 (0.50) | HRH3DRD2DRD4POLBALDH1A1 | |
| SCHEMBL6374374 | 0.87 | HRH3 (0.54) | HRH3POLBBTKPPARAESR1 | |
| SCHEMBL64181 | 0.85 | ALDH1A1 (0.49) | HRH3DRD2DRD4POLBALDH1A1 | |
| SCHEMBL6134997 | 0.84 | HRH3 (0.47) | HRH3PDE4DPDE7AALDH1A1FGFR1 | |
| SCHEMBL6132470 | 0.83 | HRH3 (0.45) | HRH3DRD2DRD4PDE4DPDE7A | |
| SCHEMBL6369297 | 0.83 | HRH3 (0.46) | HRH3DRD2DRD4POLBALDH1A1 | |
| SCHEMBL6369956 | 0.81 | HRH3 (0.45) | HRH3 | |
| SCHEMBL7339724 | 0.80 | ALDH1A1 (0.52) | HRH3PDE4DPDE7AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014685-A1 | New compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014685-A1 | New compound | MAN2B1, MAN2A1, MANBA | HRH3 1521/4885DRD2 4443/4885DRD4 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.