Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.61 |
| ▸ | LOX | P28300 | 2/20 | 0.61 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964822 | 0.86 | LOXL2 (0.61) | LOXL2LOXPLA2G7FFAR1MAOB | |
| SCHEMBL6194039 | 0.79 | FFAR1 (0.42) | LOXL2LOXLTA4HPLA2G7PDE2A | |
| SCHEMBL805488 | 0.77 | LOXL2 (0.69) | LOXL2LOXFFAR1NOS2 | |
| Hydrochloric Acid SCHEMBL4833877 | 0.77 | LOXL2 (0.54) | LOXL2LOXPLA2G7PDE2AFFAR1 | |
| SCHEMBL29223016 | 0.77 | LOXL2 (0.54) | LOXL2LOXPLA2G7FFAR1MAOB | |
| SCHEMBL178404 | 0.76 | LOXL2 (0.62) | LOXL2LOXFFAR1 | |
| SCHEMBL501711 | 0.76 | MAOB (0.60) | LOXL2LOXMAOB | |
| SCHEMBL2224895 | 0.76 | LOXL2 (0.67) | LOXL2LOXPLA2G7GRM2FFAR1 | |
| SCHEMBL130180 | 0.76 | LOXL2 (0.67) | LOXL2LOXPLA2G7GRM2FFAR1 | |
| SCHEMBL2092744 | 0.76 | LOXL2 (0.67) | LOXL2LOXFFAR1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507940-B | Heterocyclic compounds | 武田药品工业株式会社 | 2017-01-25 | — | — | CN | disclosed |
| CN-100334085-C | Quinuclidine compound and medicine containing the same as active ingredient | EISAI R & D CO LTD (JP) | 2007-08-29 | — | — | CN | disclosed |
| EP-1217001-B1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | EISAI CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6599917-B1 | A squalene-synthesizing enzyme inhibitor, a cholesterol biosynthesis inhibitor and a triglyceride biosynthesis inhibitor | EISAI CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| CN-1377349-A | Quinuclidine compound and medicine containing the same as active ingredient | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1217001-A1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |