Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 14/20 | 0.61 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.61 |
| ▸ | CTSD | P07339 | 2/20 | 0.57 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6377728 | 1.00 | BACE1 (0.61) | BACE1BACE2CTSDKISS1ROPRM1 | |
| SCHEMBL29772150 | 0.94 | BACE1 (0.62) | BACE1BACE2CTSDOPRM1OPRD1 | |
| SCHEMBL31307282 | 0.94 | BACE1 (0.58) | BACE1BACE2CTSDKISS1ROPRM1 | |
| SCHEMBL29860570 | 0.94 | OPRM1 (0.60) | BACE1BACE2CTSDKISS1ROPRM1 | |
| SCHEMBL30717710 | 0.92 | BACE1 (0.56) | BACE1BACE2CTSD | |
| SCHEMBL30974019 | 0.92 | BACE1 (0.57) | BACE1BACE2CTSDOPRM1OPRD1 | |
| SCHEMBL29860042 | 0.90 | BACE1 (0.57) | BACE1BACE2CTSDOPRM1OPRD1 | |
| SCHEMBL31208252 | 0.90 | BACE1 (0.63) | BACE1BACE2CTSDKISS1ROPRM1 | |
| SCHEMBL30717683 | 0.90 | BACE1 (0.61) | BACE1BACE2CTSDKISS1R | |
| SCHEMBL31208240 | 0.89 | BACE1 (0.64) | BACE1BACE2CTSDKISS1ROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542929-B1 | GLYCOGEN BIOSYNTHETIC ENZYMES IN PLANTS | CALGENE LLC (US) | 2005-08-10 | — | — | EP | disclosed |
| US-6538181-B1 | Methods and compositions which modify the biosynthesis and degradation pathways of reserve polysaccharides in plants; transgenic plants; Amylases; Transferases; Synthases, ADP-Glucose pyrophosphorylase | CALGENE LLC | 2003-03-25 | — | — | US | disclosed |
| US-5969214-A | TRANSGENIC PLANTS WHICH MODIFY THE BIOSYNTHESIS AND DEGRADATION PATHWAYS OF RESERVE POLYSACCHARIDES IN PLANTS. | CALGENE, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| US-5750875-A | MODIFICATION OF BIOSYNTHESIS AND DEGRADATION PATHWAYS OF RESERVE POLYSACCHARIDES IN PLANTS | MONSANTO COMPANY | 1998-05-12 | — | — | US | disclosed |
| US-5349123-A | Glycogen biosynthetic enzymes in plants | CALGENE, INC. (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0542929-A4 | GLYCOGEN BIOSYNTHETIC ENZYMES IN PLANTS | — | 1993-09-01 | — | — | EP | disclosed |
| EP-0486683-A4 | PRODUCTION OF CYCLODEXTRINS IN TRANSGENIC PLANTS | — | 1993-07-14 | — | — | EP | disclosed |
| EP-0542929-A1 | GLYCOGEN BIOSYNTHETIC ENZYMES IN PLANTS | CALGENE, INC. (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992011382-A1 | GLYCOGEN BIOSYNTHETIC ENZYMES IN PLANTS | CALGENE, INC. (US) | 1992-07-09 | — | — | WO | disclosed |
| EP-0486683-A1 | PRODUCTION OF CYCLODEXTRINS IN TRANSGENIC PLANTS | CALGENE, INC. (US) | 1992-05-27 | — | — | EP | disclosed |
| WO-1991019808-A1 | PRODUCTION OF CYCLODEXTRINS IN TRANSGENIC PLANTS | CALGENE, INC. (US) | 1991-12-26 | — | — | WO | disclosed |