⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602409 | 0.76 | — | — | |
| SCHEMBL4557229 | 0.76 | PAOX (0.56) | — | |
| SCHEMBL23798277 | 0.76 | — | — | |
| SCHEMBL5144336 | 0.72 | — | — | |
| SCHEMBL2333897 | 0.69 | — | — | |
| SCHEMBL11804666 | 0.69 | — | — | |
| SCHEMBL23074346 | 0.67 | — | — | |
| SCHEMBL7107896 | 0.67 | — | — | |
| SCHEMBL8377216 | 0.67 | — | — | |
| SCHEMBL2396665 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478550-B | Tricyclic pyrrolo [2,3-d ] pyrimidinone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-11-24 | — | — | CN | claimed |
| CN-114478550-A | Tricyclic pyrrolo [2,3-d ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-05-13 | — | — | CN | claimed |
| CN-114478550-B | Tricyclic pyrrolo [2,3-d ] pyrimidinone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-11-24 | — | — | CN | disclosed |
| CN-114478550-A | Tricyclic pyrrolo [2,3-d ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-05-13 | — | — | CN | disclosed |
| US-8119364-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-21 | — | — | US | disclosed |
| CN-101312967-B | As 5-HT4Carbamate compounds of receptor agonists | THERAVANCE INC | 2011-08-24 | — | — | CN | disclosed |
| US-20100304430-A1 | Methods for Generating Analogs of Coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-7727738-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-06-01 | — | — | US | disclosed |
| CN-101312967-A | As 5-HT4Carbamate compounds of receptor agonists | THERAVANCE INC (US) | 2008-11-26 | — | — | CN | disclosed |
| CN-101163701-A | Quinolinone compounds as 5-HT 4 receptor agonists | THERAVANCE INC (US) | 2008-04-16 | — | — | CN | disclosed |
| US-20070128683-A1 | Metabolic delivery of coenzyme A analogs | NATIONAL SCIENCE FOUNDATION | 2007-06-07 | — | — | US | disclosed |
| US-6967216-B2 | Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor | ASTRAZENECA AB (SE) | 2005-11-22 | — | — | US | disclosed |
| US-20030225097-A1 | Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor | ASTRAZENECA AB (SE) | 2003-12-04 | — | — | US | disclosed |
| EP-1278739-A1 | AMINO SUBSTITUTED DIBENZOTHIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS MEDIATED BY THE NP Y5 RECEPTOR | AstraZeneca AB (SE) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001085714-A1 | AMINO SUBSTITUTED DIBENZOTHIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS MEDIATED BY THE NP Y5 RECEPTOR | ASTRAZENECA AB (SE) | 2001-11-15 | — | — | WO | disclosed |
| CN-1194274-A | Cross-linked polymer | MITSUI CHEMICALS CO (JP) | 1998-09-30 | — | — | CN | disclosed |