⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969205 | 0.79 | — | — | |
| SCHEMBL2208010 | 0.72 | TSHR (0.39) | — | |
| SCHEMBL9843584 | 0.72 | — | — | |
| SCHEMBL608733 | 0.70 | — | — | |
| Thiourea SCHEMBL28113885 | 0.70 | — | — | |
| SCHEMBL8377216 | 0.69 | — | — | |
| SCHEMBL12019019 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL11854035 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL2205880 | 0.69 | — | — | |
| Bromide SCHEMBL10873565 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580710-B2 | Pesticidal active mixtures comprising aminothiazoline compounds | BASF SE (DE) | 2013-11-12 | — | — | US | disclosed |
| US-8198230-B2 | Synthetic mimics of mammalian cell surface receptors: method and compositions | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110224075-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | BASF SE (DE) | 2011-09-15 | — | — | US | disclosed |
| US-20020143011-A1 | Tri-substituted phenyl derivatives and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED | 2002-10-03 | — | — | US | disclosed |
| EP-0766670-B1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH R&D LTD (GB) | 2002-03-27 | — | — | EP | disclosed |
| EP-0766673-B1 | SUBSTITUTED OXIME DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH CHIROSCIENCE LTD (GB) | 2002-01-30 | — | — | EP | disclosed |
| US-20010034450-A1 | Tetra-substituted phenyl derivatives and processes for their preparation | ALEXANDER RIKKI PETER (GB) | 2001-10-25 | — | — | US | disclosed |
| US-6297264-B1 | E.G., 4-(2-BENZYLOXY-2-(3-CYCLOPENTYLOXY-4-METHOXYPHENYL)ETHYL)PYRID INE; PHOSPHODIESTERASE INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-10-02 | — | — | US | disclosed |
| US-6245774-B1 | ANTIINFLAMMATORY AGENTS; BRONCHODILATOR AGENTS | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-06-12 | — | — | US | disclosed |
| US-6197792-B1 | PHOSPHODIESTERASE INHIBITOR | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |
| EP-0766669-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1997-04-09 | — | — | EP | disclosed |
| EP-0766671-A1 | TETRA-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996000215-A1 | SUBSTITUTED OXIME DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1996-01-04 | — | — | WO | disclosed |
| WO-1995035281-A1 | TRI-SUBSTITUTED PHENYL DERIVATES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995035283-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995035284-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995035285-A1 | TETRA-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |
| US-5457206-A | Reacting a 4-hydroxy-4-chloromethyl-2-(aminomethyl)thiazoline with an alkali metal compound in an inert solvents to dechlorination | ELI LILLY AND COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| US-5334725-A | 2-aminomethyl-4-exomethylenethiazoline epoxides | ELI LILLY AND COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0515121-A1 | Process for preparing intermediates to nizatidine and related compounds | ELI LILLY AND COMPANY (US) | 1992-11-25 | — | — | EP | disclosed |