Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | HTR7 | P34969 | 4/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 3/20 | 0.57 |
| ▸ | HTR6 | P50406 | 3/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR5A | P47898 | 1/20 | 0.57 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376821 | 0.86 | AURKA (0.60) | KDM4EMAPTMEN1KMT2AHTR7 | |
| SCHEMBL27594856 | 0.83 | MEN1 (0.59) | KDM4EMAPTMEN1KMT2AHTR7 | |
| SCHEMBL28122002 | 0.78 | KMT2A (0.54) | KDM4EMAPTMEN1KMT2AHTR7 | |
| SCHEMBL6370032 | 0.78 | MEN1 (0.55) | KDM4EMAPTMEN1KMT2AHTR7 | |
| SCHEMBL12762818 | 0.76 | MEN1 (0.59) | KDM4EMAPTMEN1KMT2AHTR7 | |
| SCHEMBL18229768 | 0.76 | MEN1 (0.65) | KDM4EMAPTMEN1KMT2AHTR7 | |
| SCHEMBL273592 | 0.75 | IDO1 (0.53) | KDM4EMAPTMEN1KMT2AIDO1 | |
| SCHEMBL1515596 | 0.74 | MEN1 (0.63) | KDM4EMAPTMEN1KMT2AHTR7 | |
| SCHEMBL141724 | 0.73 | MEN1 (1.00) | KDM4EMAPTMEN1KMT2AHTR7 | |
| SCHEMBL9480941 | 0.73 | MEN1 (1.00) | KDM4EMAPTMEN1KMT2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100349905-C | Ligands for use in catalytic processes | EIDGENOESS TECH HOCHSCHULE (CH) | 2007-11-21 | — | — | CN | disclosed |
| US-20050107608-A1 | Ligands for use in catalytic processes | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH ETHZ (CH) | 2005-05-19 | — | — | US | disclosed |
| CN-1599743-A | Ligands for use in catalytic processes | EIDGENOESS TECH HOCHSCHULE (CH) | 2005-03-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107608-A1 | Ligands for use in catalytic processes | PNKP, ITPA, PLCG2 | KDM4E 3430/4885MAPT 4672/4885MEN1 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.