Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPX4 | P36969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594856 | 0.83 | MEN1 (0.59) | KMT2AMEN1KDM4EMAPTADRB2 | |
| SCHEMBL6377997 | 0.78 | KDM4E (0.57) | KMT2AMEN1KDM4EMAPTADRB2 | |
| SCHEMBL6376821 | 0.78 | AURKA (0.60) | KMT2AMEN1KDM4EMAPTADRB2 | |
| Hydrochloric Acid SCHEMBL2274556 | 0.74 | MEN1 (0.64) | KMT2AMEN1KDM4EMAPTADRB2 | |
| SCHEMBL29986234 | 0.71 | KDM4E (0.55) | KMT2AMEN1KDM4EMAPTADRB2 | |
| SCHEMBL141724 | 0.70 | MEN1 (1.00) | KMT2AMEN1KDM4EMAPTADRB2 | |
| SCHEMBL9480941 | 0.70 | MEN1 (1.00) | KMT2AMEN1KDM4EMAPTADRB2 | |
| SCHEMBL6370032 | 0.70 | MEN1 (0.55) | KMT2AMEN1KDM4EMAPTADRB2 | |
| SCHEMBL2770168 | 0.70 | MEN1 (0.65) | KMT2AMEN1KDM4EMAPTADRB2 | |
| SCHEMBL27594857 | 0.70 | MEN1 (0.55) | KMT2AMEN1KDM4EMAPTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432234-A | Method for preparing 1-phenylacetyl-beta-carboline derivatives | 中国药科大学 | 2017-02-22 | — | — | CN | disclosed |