SCHEMBL637804

SCHEMBL637804

Nc1ccccc1-n1ccnc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.61
GAA P10253 2/20 0.57
KDM4E B2RXH2 1/20 0.57
CYP3A4 P08684 6/20 0.56
CYP1A2 P05177 4/20 0.56
CYP2D6 P10635 4/20 0.56
CYP2C9 P11712 4/20 0.56
CYP2C19 P33261 4/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
LMNA P02545 3/20 0.56
MAPT P10636 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
MAPK1 P28482 2/20 0.56
ALDH1A1 P00352 1/20 0.56
PMP22 Q01453 1/20 0.56
TSHR P16473 3/20 0.47
ALOX15 P16050 1/20 0.47
CYP11B2 P19099 3/20 0.46
CYP19A1 P11511 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16382293 0.85 IDO1 (0.73) IDO1GAACYP3A4CYP1A2CYP2D6
SCHEMBL31408101 0.85 IDO1 (0.73) IDO1GAACYP3A4CYP1A2CYP2D6
SCHEMBL8590444 0.85 CYP3A4 (0.54) IDO1GAAKDM4ECYP3A4CYP1A2
SCHEMBL28287055 0.79 IDO1 (0.66) IDO1GAACYP3A4CYP1A2CYP2D6
SCHEMBL8469809 0.79 IDO1 (0.66) IDO1GAAKDM4ECYP3A4CYP1A2
SCHEMBL9426117 0.78 IDO1 (0.53) IDO1GAACYP3A4CYP1A2CYP2D6
SCHEMBL24026460 0.78 CYP11B1 (0.49) IDO1GAAKDM4ECYP3A4CYP1A2
SCHEMBL28484926 0.78 IDO1 (0.63) IDO1GAACYP3A4CYP1A2CYP2D6
SCHEMBL28493083 0.78 IDO1 (0.63) IDO1GAACYP3A4CYP1A2CYP2D6
SCHEMBL21805951 0.77 IDO1 (0.53) IDO1GAACYP3A4CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730982-A Bactericide and preparation method thereof 广东灵思妙用智能科技有限公司 2023-09-12 CN claimed
CN-116606530-A Halogen-free flame-retardant epoxy resin prepreg and preparation method thereof 苏州万润绝缘材料有限公司 2023-08-18 CN claimed
CN-114773598-A Ionic type hypercrosslinked porous polymer and preparation method thereof 南通斐腾新材料科技有限公司 2022-07-22 CN claimed
CN-101910175-A N-phenylimidazo [1,2-a ] pyridine-2-carboxamide compounds, preparation and therapeutic use thereof SANOFI AVENTIS 2010-12-08 CN claimed
EP-0677540-B1 Process for the preparation of polyurethane foams in the presence of amino alkyl or aminophenyl imidazoles as catalysts, as well as the use of these catalysts for the preparation of polyisocyanate-polyaddition products BASF AG (DE) 1999-01-27 EP claimed
US-5786402-A PRODUCING FLEXIBLE FOAM WITH REDUCED ODOR AND REDUCED FOGGING VALUE BASF AKTIENGESELLSCHAFT (DE) 1998-07-28 US claimed
EP-0677540-A2 Process for the preparation of polyurethane foams in the presence of amino alkyl or aminophenyl imidazoles as catalysts, as well as the use of these catalysts for the preparation of polyisocyanate-polyaddition products BASF AKTIENGESELLSCHAFT (DE) 1995-10-18 EP claimed
JP-8041157-A None JP disclosed
US-11993729-B2 Chemical mechanical polishing composition BASF SE (DE) 2024-05-28 US disclosed
EP-3481878-B1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-05-22 EP disclosed
EP-4312924-A1 WOUND CARE PRODUCT WITH INTEGRATED SENSOR TECHNOLOGY FOR DETERMINING WOUND DATA KOB GmbH (DE) 2024-02-07 EP disclosed
CN-115141185-B Coumarin-pyrazole derivative fluorescent probe and preparation method and application thereof 河南理工大学 2023-12-29 CN disclosed
CN-116887794-A Wound care product with integrated sensor for determining wound data 科博有限责任公司 2023-10-13 CN disclosed
US-4198508-A CYCLIZATION OF 1-(2-ACYLAMINOPHENYL)IMIDAZOLES USING PHOSPHORUS OXYCHLORIDE OR POLYPHOSPHORIC ACID WESTWOOD PHARMACEUTICALS INC. (US) 1980-04-15 US disclosed
US-4197403-A ANTIINFLAMMATORY, IMMUNOSUPPRESSIVE, FUNGICIDE WESTWOOD PHARMACEUTICALS INC. (US) 1980-04-08 US disclosed
US-4191766-A 4-(SUBSTITUTED PHENYL OR ANILINO)IMIDAZO(1,2-A)QUINOXALINES WESTWOOD PHARMACEUTICALS, INC. (US) 1980-03-04 US disclosed
US-4191767-A Method for treating fungal infection in mammals with imidazo [1,2-a]quinoxalines WESTWOOD PHARMACEUTICALS, INC. (US) 1980-03-04 US disclosed
US-4172947-A IMMUNOSUPRESSANTS, AMTIIMFLAMMATORY AGENTS, FUNGICIDES WESTWOOD PHARMACEUTICALS, INC. (US) 1979-10-30 US disclosed
US-4160097-A INTERMEDIATES FOR FUNGICIDAL AND ANTIINFLAMMATORY 4-SUBSTITUTED IMIDAZO(1,2-A)QUINOXALINES WESTWIND PHARMACEUTICALS, INC. (US) 1979-07-03 US disclosed
US-4006243-A FUNGICIDE, BACTERICIDE, YEAST SCHERING AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed