Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.81 |
| ▸ | FAP | Q12884 | 1/20 | 0.74 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.74 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.74 |
| ▸ | PREP | P48147 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376864 | 0.90 | DPP4 (1.00) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL6377059 | 0.90 | DPP4 (0.79) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL5803394 | 0.89 | DPP4 (0.87) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL5803813 | 0.89 | DPP4 (0.87) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL5803391 | 0.89 | DPP4 (0.87) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL5789336 | 0.88 | DPP4 (0.75) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL29120565 | 0.88 | DPP4 (0.82) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL29120560 | 0.88 | DPP4 (0.82) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL27228555 | 0.88 | DPP4 (0.75) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL27228553 | 0.87 | DPP4 (0.74) | DPP4FAPDPP8DPP9PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137635-B1 | N-SUBSTITUTED 2-CYANOPYRROLIDINES | NOVARTIS AG (CH) | 2005-10-19 | — | — | EP | claimed |