Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15627219 | 1.00 | SLC22A6 (0.57) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL15627218 | 1.00 | SLC22A6 (0.57) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL10192957 | 1.00 | SLC22A6 (0.57) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL8665993 | 1.00 | SLC22A6 (0.57) | SLC22A6GPR84MAPTGABRR1LMNA | |
| Water SCHEMBL30958791 | 0.98 | SLC22A6 (0.55) | SLC22A6GPR84MAPTGABRR1LMNA | |
| Calcium SCHEMBL30345478 | 0.98 | SLC22A6 (0.55) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL29441846 | 0.88 | SLC22A6 (0.44) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL55046 | 0.87 | — | — | |
| SCHEMBL265475 | 0.87 | — | — | |
| SCHEMBL27643 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945560-A | GPR119 agonists | 卡尔优普公司 | 2022-08-26 | — | — | CN | claimed |
| EP-2348063-B1 | BIODEGRADABLE POLYESTERS AND PREPARING METHOD THEREOF | KINGFA SCIENCE & TECHNOLOGY CO (CN) | 2020-04-29 | — | — | EP | claimed |
| EP-2185713-B1 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | PFIZER PROD INC (US) | 2014-09-10 | — | — | EP | claimed |
| EP-1274401-B2 | STABLE PHARMACEUTICAL COMPOSITIONS CONTAINING 7-SUBSTITUTED-3,5-DIHYDROXYHEPTANOIC ACIDS OR 7-SUBSTITUTED-3,5-DIHYDROXYHEPTENOIC ACIDS | TEVA PHARMA (IL) | 2014-08-13 | — | — | EP | claimed |
| US-8557945-B2 | Kind of biodegradable polyester and its preparation method | Kingfa Science & Technology Co., Ltd (CN) | 2013-10-15 | — | — | US | claimed |
| EP-2382970-B1 | Stable Pharmaceutical Compositions Containing 7-Substituted-3,5-Dihydroxyheptanoic Acids or 7-Substituted-3,5-Dihydroxyheptenoic Acids | TEVA PHARMA (IL) | 2013-01-09 | — | — | EP | claimed |
| US-8148324-B2 | Aldolases, nucleic acids encoding them; improving thermal stability of enzyme; biosynthesis of atorvastatin, rosuvastatin, fluvastatin starting from e.g. acetaldehyde and chloroacetaldehyde, using enzyme 2-deoxyribose-5-phosphate aldolase (DERA) to form pyran intermediate | VERENIUM CORPORATION (US) | 2012-04-03 | — | — | US | claimed |
| EP-1274401-B1 | STABLE PHARMACEUTICAL COMPOSITIONS CONTAINING 7-SUBSTITUTED-3,5-DIHYDROXYHEPTANOIC ACIDS OR 7-SUBSTITUTED-3,5-DIHYDROXYHEPTENOIC ACIDS | TEVA PHARMA (IL) | 2011-09-14 | — | — | EP | claimed |
| US-20110190468-A1 | KIND OF BIODEGRADABLE POLYESTER AND ITS PREPARATION METHOD | KINGFA SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2011-08-04 | — | — | US | claimed |
| EP-2348063-A1 | BIODEGRADABLE POLYESTERS AND PREPARING METHOD THEREOF | Kingfa Science & Technology Co., Ltd. (CN) | 2011-07-27 | — | — | EP | claimed |
| EP-2185713-A2 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | Pfizer Products Inc. (US) | 2010-05-19 | — | — | EP | claimed |
| WO-2009019561-A2 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2009-02-12 | — | — | WO | claimed |
| US-20080289056-A1 | CHEMOENZYMATIC METHODS FOR THE SYNTHESIS OF STATINS AND STATIN INTERMEDIATES | VERENIUM CORPORATION (US) | 2008-11-20 | — | — | US | claimed |
| US-7414119-B2 | Aldolases, nucleic acids encoding them and methods for making and using them | VERENIUM CORPORATION (US) | 2008-08-19 | — | — | US | claimed |
| EP-1625223-A2 | CHEMOENZYMATIC METHODS FOR THE SYNTHESIS OF STATINS AND STATIN INTERMEDIATES | Diversa Corporation (US) | 2006-02-15 | — | — | EP | claimed |
| US-20050153407-A1 | Chemoenzymatic methods for the synthesis of statins and stain intermediates | VERENIUM CORPORATION | 2005-07-14 | — | — | US | claimed |
| WO-2004027075-A2 | CHEMOENZYMATIC METHODS FOR THE SYNTHESIS OF STATINS AND STAIN INTERMEDIATES | DIVERSA CORPORATION (US) | 2004-04-01 | — | — | WO | claimed |
| US-5266707-A | Anticholesterol | FUJIREBIO INC. (JP) | 1993-11-30 | — | — | US | claimed |
| EP-0539709-A1 | 3,5-Dihydroxyheptanoic acid derivatives and lactones thereof as HMG-CoA reductase inhibitors | FUJIREBIO Inc. (JP) | 1993-05-05 | — | — | EP | claimed |
| US-4775681-A | Method of treating fungal infections with trans-6-[2-substitutedpyrrol-1-yl)alkyl]-4-hydroxypyran-2-ones | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | claimed |