Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15627219 | 1.00 | SLC22A6 (0.57) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL15627218 | 1.00 | SLC22A6 (0.57) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL10192957 | 1.00 | SLC22A6 (0.57) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL637869 | 1.00 | SLC22A6 (0.57) | SLC22A6GPR84MAPTGABRR1LMNA | |
| Water SCHEMBL30958791 | 0.98 | SLC22A6 (0.55) | SLC22A6GPR84MAPTGABRR1LMNA | |
| Calcium SCHEMBL30345478 | 0.98 | SLC22A6 (0.55) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL29441846 | 0.88 | SLC22A6 (0.44) | SLC22A6GPR84MAPTGABRR1LMNA | |
| SCHEMBL55046 | 0.87 | — | — | |
| SCHEMBL265475 | 0.87 | — | — | |
| SCHEMBL27643 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4316537-A | — | — | None | — | — | JP | disclosed |
| US-9296702-B2 | Rosuvastatin enantiomer compounds | SCALLEN, MICHAEL | 2016-03-29 | — | — | US | disclosed |
| US-9296702-B2 | Rosuvastatin enantiomer compounds | SCALLEN, MICHAEL | 2016-03-29 | — | — | US | disclosed |
| US-20140243528-A1 | Rosuvastatin Enantiomer Compounds | SCALLEN, MICHAEL | 2014-08-28 | — | — | US | disclosed |
| US-20140243528-A1 | Rosuvastatin Enantiomer Compounds | SCALLEN, MICHAEL | 2014-08-28 | — | — | US | disclosed |
| US-8729092-B2 | Rosuvastatin enantiomer compounds | SCALLEN, MICHAEL | 2014-05-20 | — | — | US | disclosed |
| US-8729092-B2 | Rosuvastatin enantiomer compounds | SCALLEN, MICHAEL | 2014-05-20 | — | — | US | disclosed |
| US-20140088126-A1 | Rosuvastatin Enantiomer Compounds | SCALLEN, MICHAEL | 2014-03-27 | — | — | US | disclosed |
| US-20140088126-A1 | Rosuvastatin Enantiomer Compounds | SCALLEN, MICHAEL | 2014-03-27 | — | — | US | disclosed |
| US-5849749-A | 6-(hydroxymethyl-ethyl)pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| JP-H04316537-A | OPTICALLY ACTIVE 3,5-ANTI-DIHYDROXYCARBOXYLIC ACID ESTER DERIVATIVE | CHISSO CORP | 1992-11-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243528-A1 | Rosuvastatin Enantiomer Compounds | HMGCR, LDLR, PCSK9 | SLC22A6 2181/4885GPR84 1867/4885MAPT 27/4885 |
| US-20140088126-A1 | Rosuvastatin Enantiomer Compounds | HMGCR, PCSK9, CYP3A5 | SLC22A6 2271/4885GPR84 1768/4885MAPT 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.