Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.68 |
| ▸ | PNMT | P11086 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3122743 | 0.88 | CA2 (0.53) | TAAR1PNMTALOX15IGF1RRECQL | |
| SCHEMBL184185 | 0.82 | TAAR1 (1.00) | TAAR1PNMTSIGMAR1ALOX15IGF1R | |
| Trifluoroacetic Acid SCHEMBL29484054 | 0.81 | TAAR1 (0.64) | TAAR1FFAR1IDO1TDP1MEN1 | |
| Trifluoroacetic Acid SCHEMBL29484053 | 0.81 | TAAR1 (0.64) | TAAR1FFAR1IDO1TDP1MEN1 | |
| Trifluoroacetic Acid SCHEMBL3399696 | 0.81 | SLC6A4 (0.46) | TAAR1PNMTFFAR1IDO1KMT2A | |
| Trifluoroacetic Acid SCHEMBL3116313 | 0.81 | GLA (0.56) | TAAR1PNMTFFAR1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL30496706 | 0.80 | TAAR1 (0.95) | TAAR1PNMTSIGMAR1ALOX15IGF1R | |
| Hydrochloric Acid SCHEMBL2540390 | 0.80 | TAAR1 (0.95) | TAAR1PNMTSIGMAR1ALOX15IGF1R | |
| Trifluoroacetic Acid SCHEMBL6379102 | 0.79 | TAAR1 (0.69) | TAAR1PNMTTRPV1MEN1KMT2A | |
| Dopamine SCHEMBL7078952 | 0.79 | KDM4E (0.70) | TAAR1ALOX15IGF1RRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150946-B1 | ARYLALKANOYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA GMBH (DE) | 2005-03-30 | — | — | EP | disclosed |