Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.69 |
| ▸ | EGFR | P00533 | 4/20 | 0.69 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.69 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | BCR | P11274 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6387094 | 0.89 | SRC (0.70) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6382448 | 0.86 | SRC (0.71) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6386277 | 0.86 | SRC (0.66) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6383067 | 0.84 | EGFR (0.69) | SRCEGFRERBB2 | |
| SCHEMBL6380454 | 0.84 | SRC (0.74) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6379607 | 0.84 | SRC (0.68) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6380332 | 0.82 | SRC (0.85) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6384845 | 0.82 | SRC (0.61) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL1894458 | 0.82 | SRC (1.00) | SRCEGFRERBB2ABL1BCR | |
| SCHEMBL6997074 | 0.81 | SRC (0.56) | SRCEGFRERBB2ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263503-B1 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | WYETH CORP (US) | 2005-11-02 | — | — | EP | claimed |
| EP-0973746-B1 | SUBSTITUTED 3-CYANO QUINOLINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | claimed |