Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | BCR | P11274 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384135 | 0.90 | SRC (0.60) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6383157 | 0.89 | SRC (0.57) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6387094 | 0.88 | SRC (0.70) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6384073 | 0.86 | EGFR (0.70) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6382110 | 0.86 | SRC (0.50) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5254965 | 0.84 | SRC (0.67) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6381779 | 0.83 | SRC (0.57) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL4450581 | 0.82 | SRC (0.80) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6382122 | 0.82 | EGFR (0.69) | SRCEGFRERBB2PRKCQ | |
| SCHEMBL6380340 | 0.81 | SRC (0.69) | SRCABL1BCREGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117659-B1 | SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS | WYETH CORP (US) | 2003-12-03 | — | — | EP | claimed |