Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.47 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862152 | 0.99 | MCHR1 (0.47) | MCHR1MCHR2BTKPKMLMNA | |
| SCHEMBL6348132 | 0.93 | MCHR1 (0.45) | MCHR1MCHR2BTKPKMLMNA | |
| SCHEMBL6380408 | 0.82 | MCHR1 (0.64) | MCHR1MCHR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5860816 | 0.81 | MCHR1 (0.71) | MCHR1MCHR2EPHX1 | |
| SCHEMBL5861903 | 0.81 | MCHR1 (0.70) | MCHR1MCHR2LMNAEPHX1 | |
| SCHEMBL5860819 | 0.80 | MCHR1 (0.68) | MCHR1MCHR2BTKLMNAALDH1A1 | |
| SCHEMBL5860936 | 0.78 | MCHR1 (0.41) | MCHR1BTKALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6374843 | 0.77 | NPSR1 (0.45) | MCHR1BTKLMNAALDH1A1KDM4E | |
| SCHEMBL5862038 | 0.76 | MCHR1 (0.64) | MCHR1MCHR2EPHX1 | |
| SCHEMBL5860855 | 0.73 | ALDH1A1 (0.41) | MCHR1MCHR2BTKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187279-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBVIE INC. | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187279-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | MCHR1 1/4885MCHR2 2/4885BTK 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.