Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957710 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KMT2ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL2967449 | 0.85 | PDE1A (0.62) | ALDH1A1KMT2ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL6383655 | 0.84 | PDE4A (0.35) | ALDH1A1KMT2ASMN1; SMN2ADORA2B | |
| SCHEMBL2961214 | 0.82 | POLB (0.64) | ALDH1A1KMT2ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL5791764 | 0.82 | ALDH1A1 (0.34) | ALDH1A1KMT2ASMN1; SMN2MEN1TSHR | |
| SCHEMBL6381761 | 0.82 | SMN1; SMN2 (0.60) | ALDH1A1KMT2ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL6380785 | 0.82 | KMT2A (0.52) | ALDH1A1KMT2ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL5718879 | 0.81 | POLB (0.65) | ALDH1A1KMT2ASMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL2952786 | 0.78 | BRD4 (0.59) | ALDH1A1KMT2APOLBMEN1HPGD | |
| SCHEMBL6379880 | 0.76 | BRD4 (0.54) | ALDH1A1KMT2ASMN1; SMN2ADORA2BRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1557165-A1 | COMBINATION DRUG | Eisai Co., Ltd. (JP) | 2005-07-27 | — | — | EP | disclosed |