Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 2/20 | 0.48 |
| ▸ | MC4R | P32245 | 4/20 | 0.45 |
| ▸ | MC3R | P41968 | 4/20 | 0.45 |
| ▸ | MC1R | Q01726 | 4/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380846 | 1.00 | BDKRB2 (0.48) | BDKRB2MC4RMC3RMC1RMCL1 | |
| SCHEMBL6380857 | 1.00 | BDKRB2 (0.48) | BDKRB2MC4RMC3RMC1RMCL1 | |
| SCHEMBL26604823 | 0.88 | ABCB1 (0.52) | BDKRB2MCL1ABCB1UCHL1AGTR2 | |
| SCHEMBL3179881 | 0.88 | ABCB1 (0.52) | BDKRB2MCL1ABCB1UCHL1AGTR2 | |
| SCHEMBL708630 | 0.88 | ABCB1 (0.52) | BDKRB2MCL1ABCB1UCHL1AGTR2 | |
| SCHEMBL376159 | 0.88 | ABCB1 (0.52) | BDKRB2MCL1ABCB1UCHL1AGTR2 | |
| SCHEMBL1448119 | 0.88 | ABCB1 (0.52) | BDKRB2MCL1ABCB1UCHL1AGTR2 | |
| SCHEMBL7287734 | 0.88 | ABCB1 (0.52) | BDKRB2MCL1ABCB1UCHL1AGTR2 | |
| SCHEMBL949983 | 0.88 | ABCB1 (0.52) | BDKRB2MCL1ABCB1UCHL1AGTR2 | |
| SCHEMBL708628 | 0.88 | ABCB1 (0.52) | BDKRB2MCL1ABCB1UCHL1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003775-B1 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM CA LTD (CA) | 2005-03-16 | — | — | EP | disclosed |
| US-6767991-B1 | PEPTIDES AND ANALOGS THEREOF; VIRAL PROTEASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH PEPTIDES AND RIBAVIRIN | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2004-07-27 | — | — | US | disclosed |