Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.55 |
| ▸ | ANTXR2 | P58335 | 3/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | F11 | P03951 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4875707 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 | |
| SCHEMBL19090430 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 | |
| SCHEMBL14037294 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 | |
| SCHEMBL14356268 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 | |
| SCHEMBL6252668 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 | |
| SCHEMBL15814640 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 | |
| SCHEMBL14011212 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 | |
| SCHEMBL12154605 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 | |
| SCHEMBL17326916 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 | |
| SCHEMBL6252674 | 0.88 | PTPN1 (0.68) | PTPN1ANTXR2PTPN2PTPN11USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501850-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040063658-A1 | Nucleoside derivatives for treating hepatitis C virus infection | GENELABS TECHNOLOGIES, INC. | 2004-04-01 | — | — | US | disclosed |
| WO-2003093290-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063658-A1 | Nucleoside derivatives for treating hepatitis C virus infection | HAVCR2, PNP, NTPCR | PTPN1 3780/4885ANTXR2 4343/4885PTPN2 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.