Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 8/20 | 0.65 |
| ▸ | SSTR5 | P35346 | 7/20 | 0.65 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.65 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.65 |
| ▸ | SSTR3 | P32745 | 6/20 | 0.65 |
| ▸ | TACR1 | P25103 | 4/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6385509 | 0.93 | SSTR1 (0.55) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL6380947 | 0.90 | SSTR5 (0.52) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL6380615 | 0.88 | TNF (0.60) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL6381530 | 0.85 | SSTR5 (0.50) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL6382242 | 0.85 | SSTR5 (0.49) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL13005380 | 0.85 | SSTR5 (0.58) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL13088352 | 0.85 | SSTR5 (0.58) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL4587088 | 0.85 | SSTR5 (0.58) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL8992036 | 0.85 | SSTR5 (0.58) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL12729388 | 0.85 | SSTR5 (0.58) | SSTR4SSTR5SSTR1SSTR2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001961-B1 | SUBSTITUTED TETRAHYDROPYRANE DERIVATIVES AND METHOD FOR PRODUCING SAME | AVENTIS PHARMA GMBH (DE) | 2005-01-26 | — | — | EP | disclosed |
| US-6756489-B1 | PROTECTED MONOSACCHARIDES HAVING AN ALLYL PROTECTING GROUP, A SILANE-PROTECTED HYDROXY GROUP AND A CARBOXY OR AMIDE CONTAINING PROTECTIVE GROUP; EASILY MADE BY COMBINATORIAL CHEMISTRY; APPLICATIONS TO AUTOIMMUNE AND CANCER | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-06-29 | — | — | US | disclosed |