Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448097 | 0.87 | PTPN11 (0.61) | KDM4EPOLBPTPN11S1PR3PTPN1 | |
| SCHEMBL26212753 | 0.82 | KDM4E (0.52) | KDM4EPOLBPTPN11S1PR3ALDH1A1 | |
| SCHEMBL3903917 | 0.80 | KDM4E (0.60) | KDM4EPOLBALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9185455 | 0.79 | KDM4E (0.59) | KDM4EPOLBALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL8136068 | 0.79 | KDM4E (0.59) | KDM4EPOLBALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4147094 | 0.79 | KDM4E (0.59) | KDM4EPOLBALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL267614 | 0.78 | KDM4E (0.50) | KDM4EPOLBALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL503802 | 0.78 | POLB (0.70) | KDM4EPOLBALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL35211213 | 0.78 | PTPN11 (0.64) | PTPN11S1PR3PTPN1PTPN6 | |
| SCHEMBL26731143 | 0.78 | KDM4E (0.48) | KDM4EPOLBPTPN11S1PR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549958-A2 | MALDI-MATRIX | N.V. Nutricia (NL) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004023147-A2 | MALDI-MATRIX | N.V. NUTRICIA (NL) | 2004-03-18 | — | — | WO | disclosed |