SCHEMBL503802

SCHEMBL503802

COc1ccc(OC)c(C(=O)O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.70
KDM4E B2RXH2 2/20 0.70
ALDH1A1 P00352 2/20 0.70
MAPT P10636 2/20 0.68
HTT P42858 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.61
HPGD P15428 1/20 0.59
ABCG2 Q9UNQ0 1/20 0.58
HSD17B10 Q99714 1/20 0.56
HSD11B1 P28845 1/20 0.55
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
LMNA P02545 1/20 0.54
PDE4A P27815 1/20 0.54
PDE4B Q07343 1/20 0.54
PDE4C Q08493 1/20 0.54
PDE4D Q08499 1/20 0.54
AKR1C3 P42330 1/20 0.54
AKR1C2 P52895 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9185042 0.98 POLB (0.68) POLBKDM4EALDH1A1MAPTHTT
SCHEMBL4840255 0.88 ALDH1A1 (0.69) POLBKDM4EALDH1A1MAPTHTT
SCHEMBL12228747 0.86 MAPT (0.82) POLBKDM4EALDH1A1MAPTHTT
SCHEMBL27885546 0.85 SMN1; SMN2 (0.58) POLBKDM4EALDH1A1MAPTHTT
SCHEMBL1318999 0.85 CFD (0.67) POLBKDM4EALDH1A1MAPTHTT
SCHEMBL29399711 0.84 NPC1 (0.66) POLBKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL154613 0.84 NPC1 (0.66) POLBKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL2553094 0.84 NPC1 (0.66) POLBKDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL885028 0.84 MAPT (0.68) POLBKDM4EALDH1A1MAPTHTT
SCHEMBL536099 0.84 CA12 (0.55) POLBKDM4EALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-4477693-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS Korea Research Institute of Chemical Technology (KR) 2024-12-18 EP claimed
CN-118290246-B Method for preparing cynanchum bungei benzophenone 贵州省天然产物研究中心 2024-11-29 CN claimed
US-12076316-B2 Levorphanol prodrugs and processes for making and using them ZEVRA THERAPEUTICS INC. 2024-09-03 US claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118290246-A Method for preparing cynanchum bungei benzophenone 贵州省天然产物研究中心 2024-07-05 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
WO-2023195794-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS 한국화학연구원 2023-10-12 WO claimed
US-6569511-B1 Polysiloxane having a hydrophilic moiety and a lightfastness moiety; ink jet coating XEROX CORPORATION 2003-05-27 US claimed
US-20030036661-A1 2-Aroyl-4-acyl paclitaxel (taxol) analogs BRISTOL-MYERS SQUIBB COMPANY 2003-02-20 US claimed
EP-1067923-A4 2-AROYL-4-ACYL PACLITAXEL (TAXOL) ANALOGS BRISTOL MYERS SQUIBB CO (US) 2002-11-13 EP claimed
US-6398857-B1 ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS XEROX CORPORATION 2002-06-04 US claimed
US-6391916-B1 ANTITUMOR AGENTS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2002-05-21 US claimed
EP-1067923-A1 2-AROYL-4-ACYL PACLITAXEL (TAXOL) ANALOGS BRISTOL-MYERS SQUIBB COMPANY (US) 2001-01-17 EP claimed
WO-1999033462-A9 2-AROYL-4-ACYL PACLITAXEL (TAXOL) ANALOGS KINGSTON DAVID GEORGE IAN (US) 1999-09-30 WO claimed
WO-1999033462-A1 2-AROYL-4-ACYL PACLITAXEL (TAXOL) ANALOGS VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1999-07-08 WO claimed
EP-0533744-A1 HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS BIOCHEM PHARMA INC. (CA) 1993-03-31 EP claimed
WO-1991019725-A2 HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS BIOCHEM PHARMA INC. (CA) 1991-12-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS FGB, NR4A1, CYP2E1 POLB 1740/4885KDM4E 570/4885ALDH1A1 105/4885
US-12076316-B2 Levorphanol prodrugs and processes for making and using them OPRM1, OPRL1, OPRK1 POLB 1667/4885KDM4E 2657/4885ALDH1A1 1258/4885
US-20030036661-A1 2-Aroyl-4-acyl paclitaxel (taxol) analogs HDAC6, HDAC3, ACAT2 POLB 794/4885KDM4E 922/4885ALDH1A1 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.