⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443633 | 0.81 | CHRM2 (0.30) | — | |
| SCHEMBL11387395 | 0.80 | — | — | |
| SCHEMBL12977792 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL1471228 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL1471354 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL5945084 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL12977807 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL12978019 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL8927903 | 0.73 | — | — | |
| SCHEMBL12497230 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078264-A1 | (R)-chiral halogenated substituted N,N-bis-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2003-04-24 | — | — | US | claimed |
| US-20030050317-A1 | (R)-chiral halogenated substituted n,n-bis-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2003-03-13 | — | — | US | claimed |
| US-20030040545-A1 | (R)-Chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2003-02-27 | — | — | US | claimed |
| US-20030027826-A1 | (R)-Chiral halogenated substituted heteroaryl benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2003-02-06 | — | — | US | claimed |
| US-20020177708-A1 | (R)-chiral halogenated substituted N-benzyl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-28 | — | — | US | claimed |
| EP-1115695-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(N+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | claimed |
| WO-2000018724-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| US-11679291-B2 | Compositions and uses of Z-1-chloro-2,3,3,3-tetrafluoroprop-1-ene | THE CHEMOURS COMPANY FC, LLC (US) | 2023-06-20 | — | — | US | disclosed |
| US-10736966-B2 | Brush-poly (glycoamidoamine)-lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-08-11 | — | — | US | disclosed |
| US-20200230454-A1 | COMPOSITIONS AND USES OF Z-1-CHLORO-2,3,3,3-TETRAFLUOROPROP-1-ENE | THE CHEMOURS COMPANY FC, LLC (US) | 2020-07-23 | — | — | US | disclosed |
| EP-3668937-A1 | COMPOSITIONS AND USES OF Z-1-CHLORO-2,3,3,3-TETRAFLUOROPROP-1-ENE | The Chemours Company FC, LLC (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019036049-A1 | COMPOSITIONS AND USES OF Z-1-CHLORO-2,3,3,3-TETRAFLUOROPROP-1-ENE | THE CHEMOURS COMPANY, FC, LLC (US) | 2019-02-21 | — | — | WO | disclosed |
| WO-2018165623-A1 | USES OF FLUORINATED EPOXIDES AND NOVEL MIXTURES THEREOF | THE CHEMOURS COMPANY FC, LLC (US) | 2018-09-13 | — | — | WO | disclosed |
| US-20160067346-A1 | BRUSH-POLY (GLYCOAMIDOAMINE)-LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-03-10 | — | — | US | disclosed |
| US-20160067346-A1 | BRUSH-POLY (GLYCOAMIDOAMINE)-LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-03-10 | — | — | US | disclosed |
| WO-2010028362-A1 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| EP-1589000-A2 | (R)-Chiral halogenated 1-substitutedamino-(N+1)-alkanols useful for inhibiting cholesteryl ester transfer protein activity | Monsanto Company (US) | 2005-10-26 | — | — | EP | disclosed |